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Senior Scientist - Structural Biology (m/f/d)

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Job Details

Job ID:
14236
Category:
Research Scientist
Location:
Germany
Job Type:
On-site

We are looking for an experienced structural biologist with a background in X-ray crystallography to join the growing Structural Biology group based in Munich, Germany. In close collaboration with the various departments at Crelux you will provide structural biology support for early-stage drug discovery projects covering a wide range of target classes. Your main responsibilities will include the planning of structural biology projects and crystallization experiments, X-ray crystallography data processing and structure determination of protein-ligand complexes, and the communication of results to our clients.

Requirements

  • Planning and running structural biology client projects with a focus on structure-based drug design in early-stage drug discovery projects
  • Planning of crystallization and data collection experiments as well as the determination of X-ray crystal structures (typically protein-ligand complexes)
  • Professional written and verbal communication of scientific results in internal and external project teams
  • Careful documentation and evaluation of scientific protocols and results
  • The ability to plan work to meet planned timelines
  • Maintain an up-to-date knowledge of scientific advances in structural biology

Qualifications

  • PhD in Biology, Biochemistry, Chemistry or a related subject
  • Practical and theoretical knowledge of construct design, crystallization, and structure determination using standard software packages (in particular Global Phasing, CCP4, XDS, PyMOL and ChimeraX) running on Linux
  • Experience in any of the following areas would be highly advantageous – cryo-electron microscopy, crystallographic fragment screening, protein design
  • Experience with programming (Bash and Python), databases (SQL/MariaDB) and/or administration of Linux systems would be a strong advantage
  • Excellent interpersonal skills and the ability to work and communicate efficiently in interdisciplinary teams
  • Fluent spoken and written English and (ideally) German

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